Copenhagen, Denmark
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ESTRO 2022

Session Item

Saturday
May 07
14:15 - 15:15
Poster Station 1
05: Intra-fraction & real-time adaptation
Jan-Jakob Sonke, The Netherlands
Poster Discussion
Physics
Temporal accuracy for gated radiotherapy beams
Andreas Thoft, Sweden
PD-0234

Abstract

Temporal accuracy for gated radiotherapy beams
Authors:

Jacob Snäll1, Andreas Thoft1, Malin Kügele1,2, Anneli Edvardsson1

1Skåne University Hospital, Department of Hematology, Oncology and Radiation Physics, Lund, Sweden; 2Lund University, Department of Medical Radiation Physics, Clinical Sciences, Lund, Sweden

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Purpose or Objective

Radiotherapy (RT) can be delivered synchronized to the patient's respiratory motion, i.e. gating. The temporal accuracy for gated beams, i.e. the time from the gate signal to the beam-on/off, should be within 100 ms according to quality assurance (QA) recommendations [1]. A user-friendly QA tool was developed which through movement triggers a gating system and thereby measure temporal accuracy with high resolution in real-time.  The aim of this work was to quantify the temporal accuracy for gated RT for six linacs and two different energies.

Material and Methods

An in-house developed QA tool was used to measure the beam-on/off times for six beam-matched linacs (TrueBeam 2.5, Varian). Ten measurements per beam-on/off were performed for both 6 and 10 MV triggered by surface imaging (Catalyst, C-rad Positioning AB) clinically used for gated RT treatments. For all measurements, the integration time was set to 2000 µs and a circular region-of-interest (ROI) with a radius of 20 mm was projected on a motion platform (fig 1b) to track the motion.


The QA tool is equipped with three sources for the temporal accuracy measurements; two diodes (QED, Sun Nuclear) placed in the radiation field and a connection to the target current signal of the linac. The design of the electrical circuit is described elsewhere [2]. Each beam pulse generated is amplified and then measured with a high time resolution microcontroller unit. The first diode was used for all measurements presented, and the other two sources were used for verification only.


The beam-on/off times (ton/toffwere defined as the time between the start signal of the motion platform until the first/last beam pulse measured by the diode, corrected for a 22 ms time lag (fig 1a).  Unpaired Mann-Whitney U-tests were carried out to comparton and toff between the two energies.


Figure 1. (a) Flow charts of the beam-on/off temporal accuracy measurements. (b) The motion platform of the QA tool with the ROI projected on top together with the diodes.

Results

The temporal accuracy for each linac is presented in figure 2. For all 60 measurements, the median ton and toff were 158 and 89 ms for both 6 and 10 MV (p = 0.68 and 0.73), with a large range (fig 2). Excellent agreement was observed for the diodes and target current signal, verifying the results of the primary diode. Approximately 20% of the toff values exceeded the 100 ms recommendation with a maximum value of 140 ms. For a dose rate of 600 MU/min this would in worst-case result in 1.4 MU delivered outside the gating window.

Figure 2. Temporal accuracy for six Truebeam linacsThe dashed lines represent the median value and interquartile range.

Conclusion

The temporal accuracy was found to exceed the recommended 100 ms which emphasise the need for routine QA. The QA tool developed in this study allowed for fast non-invasive measurements of temporal accuracy in real time, independent of linac and gating system.

  1. Klein, E.E. et al. ,Med Phys,2009.36(9): p.4197-212
  2. Lempart, M. et al. ,IRBM,2016.37(3):p.144-51