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Vienna, Austria

ESTRO 2023

Session Item

Sunday
May 14
08:45 - 10:00
Strauss 2
Risk-adapted personalised brachytherapy
Artur Chyrek, Poland;
Marisol De Brabandere, Belgium
Symposium
Brachytherapy
08:45 - 09:10
Dose (de)escalation in advanced tumours: Lessons from EMBRACE I and perspectives
Maximilian Schmid, Austria
SP-0372

Abstract

Dose (de)escalation in advanced tumours: Lessons from EMBRACE I and perspectives
Authors:

Maximilian Schmid1

1Medical University of Vienna, Department of Radiation Oncology, Vienna, Austria

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Abstract Text

This presentation will summarize clinical outcome of patients treated with definitive chemo-radiation and MRI based image-guided adaptive brachytherapy for locally advanced cervical cancer within the Embrace I study. Main focus will be put on risk factors for local failure and new insights into dose-response relationships for local tumour control. Recent evidence from EMBRACE I and upcoming evidence from EMBRACE II point - beyond the current strategy of individual volumetric adaptation – towards the possibility of risk-adapted treatment and personalized dose prescription. First concepts for EMBRACE III will be outlined.