ESTRO 2023

Session Item

Monday

May 15

09:00 - 10:00

Business Suite 1-2

Education is the RTT superpower

Chair: , Ireland

Session Type: Poster Discussion

Track: RTT

Journey:

RADAR Project: pediatric patients AI-profiling, focus on clinical and psychological outcomes

Elisa Marconi, Italy

Presentation Number: PD-0733

Abstract

Abstract Title:

RADAR Project: pediatric patients AI-profiling, focus on clinical and psychological outcomes

Authors:

Elisa Marconi^1,2, Elisa Meldolesi¹, Francesco Beghella Bartoli¹, Fatjona Pupuleku Kraja³, Silvia Mariani⁴, Giulia Panza¹, Angela Mastronuzzi⁵, Antonio Ruggiero⁶, Maria Antonietta Gambacorta¹, Vincenzo Valentini¹, Mario Balducci¹, Daniela Pia Rosaria Chieffo², Silvia Chiesa¹

¹Fondazione Policlinico Universitario Agostino Gemelli IRCCS, UOC di Radioterapia Oncologica, Dipartimento Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, , Rome, Italy; ²Fondazione Policlinico Universitario Agostino Gemelli IRCCS, UOS di Psicologia Clinica, Rome, Italy; ³University Hospital Center Mother Teresa, Genitourinary Oncology Department , Tirana, Albania; ⁴Università̀ Cattolica del Sacro Cuore, UOC di Radioterapia Oncologica, Dipartimento Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, , Rome, Italy; ⁵ Ospedale Pediatrico Bambino Gesù IRCSS, Dipartimento Oncoematologia, Terapia Cellulare, Terapie Geniche e Trapianto Emopoietico, Rome, Italy; ⁶Fondazione Policlinico Universitario Agostino Gemelli IRCCS, UOC di Oncologia Pediatrica, Dipartimento della Salute della Donna, del Bambino e di Sanità Pubblica, Rome, Italy

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Purpose or Objective

Since 2020, RADAR Project was developed to enhance the pediatric radiotherapy pathway in a bio-psychosocial approach. A first-visit Multidimensional Assessment for Pediatric patients in RadioTherapy (MAP-RT) was initially introduced and it has been shown to have a high level of accuracy in predicting the need for sedation. Besides this, specific actions, such as psychological preparation and support, and specific tools (audiovisual, digital, etc.) were introduced to support the pediatric patient (PP) and their parents during the radiotherapy care path. The aim of the present study is to improve the level of personalization and management of PP care.

Material and Methods

Pediatric patients (aged 0–21 years) were enrolled in this study. The MAP-RT module consists of 28 items divided into sections, and it is composed of various standardized instruments. It was administered to pediatric patients and their families in a standardized way. Data collection of various thematic areas was completed by the radiation oncologist, psychologist, technician and nurse. In addition to MAP-RT data, age and intensive psychological interventions (IPI, 1/2 times the standard protocol of 1 intervention per week) and G2-detected toxicity were collected. Correlation matrix and multivariate analyses were carried out.

Results

A total of 100 pediatric patients were included in the study, with a mean age 7.2+-5 years (1-21 years). Correlation matrix results show that younger children and their parents reported higher anxiety levels. The anxiety level of children and parents was found to be mutually positively correlated (p<.001 ). A negative high correlation also emerges between age and distress level during the first treatment-room-exposition (Children Emotional Manifestation Scale - CEMS) (p<.001). Children with more externalized issues required more significant IPI (p<.001 ). On the multivariate analysis, no significant differences were observed based on gender. The analysis on the toxicity profile showed no significant differences between groups (age, gender).

Conclusion

These results demonstrated that the MAP-RT data can provide predictive information on the children's compliance to radiotherapy treatment, support a potential AI-driven selection of psychological interventions and optimize care for these patients.